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Published on: April 25, 2014
Acute and long-term outcome after coronary artery perforation during percutaneous coronary interventions
H Eggebrecht1, A Ritzel, C von Birgelen
1Klinik für Kardiologie, Westdeutsches Herzzentrum Essen, Universitätsklinikum Essen, Hufelandstrasse 55, 45122 Essen, Germany. holger.eggebrecht@uni-essen.de
Insights
Coronary artery perforation during percutaneous coronary interventions (PCI) is rare but serious. Non-surgical management is often successful for this complication, despite associated morbidity and mortality.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Coronary artery perforation is a rare but serious complication during percutaneous coronary interventions (PCI).
- The incidence of coronary perforation during PCI is approximately 0.3%.
Purpose of the Study:
- To review the mechanisms, management, and outcomes of coronary perforation during PCI.
- To evaluate the efficacy of non-surgical management strategies for coronary artery perforation.
Main Methods:
- Retrospective review of a database for coronary perforation cases during PCI procedures (01/1998-12/2003).
- Analysis of hospital charts, procedural reports, and coronary angiograms.
- Emphasis on perforation mechanisms, management strategies, and clinical outcomes.
Main Results:
- 19 cases of coronary perforation occurred during 6433 PCI procedures.
- Perforation frequently occurred during chronic total occlusion recanalization (63%).
- Non-surgical management was attempted in most cases (95%), with prolonged balloon inflation (53%) and stenting (32%) being common interventions. Cardiac tamponade occurred in 16% of patients, and 11% required surgical repair. Early mortality was 11%.
Conclusions:
- Coronary perforation during PCI, though rare, leads to significant morbidity and mortality.
- Non-surgical management is feasible and successful in the majority of patients.
- Effective management strategies can mitigate the risks associated with this complication.
Background:
Coronary artery perforation is a rare but serious complication of percutaneous coronary interventions (PCI).
Methods:
We reviewed our database for cases of overt coronary perforation during PCI procedures. Hospital charts, procedural reports, and coronary angiograms of these patients were reviewed, with particular emphasis on mechanisms of perforation, management of the complication, and clinical outcome.
Results:
Between 01/1998 and 12/2003, a total of 19 cases (mean age: 66+/-8 years, 13 male) of coronary perforation occurred during 6433 PCI procedures performed within this period (incidence: 0.3%). In 12/19 (63%) cases, perforation occurred during recanalisation procedures of chronic total occlusions of coronary arteries. In all but one patient, non-surgical management was attempted: 2 out of 19 (11%) patients were treated conservatively by reversal of heparin anticoagulation. Prolonged balloon inflation at the perforation site was applied in 10/19 (53%) patients. Six (32%) patients received stents (5 of them received covered stentgrafts), 3 (16%) patients developed cardiac tamponade requiring percardiocentesis, and only 2 (11%) patients underwent bailout surgical repair. There were 2 (11%) deaths early after the procedure.
Conclusion:
Coronary perforation during PCI is a rare complication, but is associated with significant morbidity and mortality. In the majority of patients, non-surgical management is both feasible and associated with a high success-rate.
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