Control of protein adsorption: molecular level structural and spatial variables

David J Vanderah1, Hongly La, Jessica Naff

  • 1Biotechnology Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland 20899-8313, USA. david.vanderah@nist.gov

Summary

Oligo(ethylene oxide)-coated gold surfaces minimize protein adsorption by constricting oligomers, creating an energy barrier. This protein rejection mechanism offers insights into surface science and biomaterial design.

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