Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Pituicytoma.

Robert J Kowalski¹, Richard A Prayson, Marc R Mayberg

¹Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

Annals of Diagnostic Pathology

|October 21, 2004

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Preventing Microglial Reactivity Protects from Acute and Progressive Neuronal Dysfunction, Motor Impairments and Sedation following Alcohol Abuse.

bioRxiv : the preprint server for biology·2025

Same author

Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss.

Cancer research communications·2025

Same author

Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer's disease.

Immunity·2025

Same author

Introduction. Advanced techniques for reconstruction following neurosurgical interventions.

Neurosurgical focus·2025

Same author

Rapid postradiation malignant transformation of a pilocytic astrocytoma in an adult with neurofibromatosis type 1: illustrative case.

Journal of neurosurgery. Case lessons·2024

Same author

Long non-coding RNA lung cancer-associated transcript-1 promotes glioblastoma progression by enhancing Hypoxia-inducible factor 1 alpha activity.

Neuro-oncology·2024

Pituicytoma, a rare pituitary tumor, can mimic adenomas. This case highlights its unique cellular features and recurrence after resection, emphasizing the need for accurate diagnosis.

Area of Science:

Neuro-oncology
Endocrinology
Surgical Pathology

Background:

Pituicytoma is a rare, low-grade neoplasm originating in the neurohypophysis.
Clinical presentation can mimic pituitary adenoma, including panhypopituitarism.

Observation:

A 52-year-old man presented with a pituitary mass and panhypopituitarism.
Histopathology revealed elongated cells in bundles, positive for S-100 and GFAP.
Negative staining for cytokeratin, synaptophysin, chromogranin, pituitary hormones, and p53 was noted.

Findings:

The tumor exhibited a low MIB-1 labeling index (1.1%).
Subtotal resection was performed, with tumor recurrence observed 11 months post-surgery.

Implications:

Related Experiment Videos

Accurate clinicopathologic diagnosis is crucial for differentiating pituicytoma from pituitary adenoma.
Understanding pituicytoma's behavior is essential for surgical and long-term management strategies.
Further review of literature and differential diagnosis is warranted for this rare entity.