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[Urinary calculi epidemiology in children]
François Cachat1, Frédéric Barbey, Jean-Pierre Guignard
1Département de pédiatrie, Unité de néphrologie pédiatrique, CHUV, Lausanne. Francois.Cachat@hospvd.ch
Insights
Pediatric urolithiasis is often caused by urinary tract infections, leading to struvite stones. Comprehensive stone analysis and biochemical testing are crucial for effective treatment and preventing kidney damage.
Area of Science:
- Pediatric Nephrology
- Urology
- Biochemistry
Context:
- Urolithiasis in pediatric patients presents unique etiological and clinical challenges.
- Understanding the composition and causes of pediatric kidney stones is essential for management.
- Urinary tract infections (UTIs) are a significant contributing factor in childhood urolithiasis.
Purpose:
- To analyze the characteristics of urolithiasis in a cohort of pediatric patients.
- To identify common stone compositions, presenting symptoms, and biochemical abnormalities.
- To highlight the importance of diagnostic investigations for preventing stone recurrence and complications.
Summary:
- A study of 40 pediatric patients revealed common symptoms like abdominal pain and UTIs.
- Struvite stones were prevalent (35%), linked to UTIs, followed by calcium-phosphate (25%) and calcium-oxalate (20%).
- Hypercalciuria was the most frequent biochemical abnormality (>50%), underscoring the need for thorough investigations.
Impact:
- Emphasizes the critical role of stone analysis and biochemical evaluation in pediatric urolithiasis management.
- Suggests extra-corporeal shock wave lithotripsy as a viable treatment for non-spontaneous stone passage.
- Aims to reduce stone recurrence and prevent progression to chronic kidney disease in children.
Abstract:
We identified 40 pediatric patients with urolithiasis. There were 27 boys and 13 girls. Initial symptoms were abdominal pain, with or without microscopic hematuria in 40% of the cases, and urinary tract infection/pyelonephritis in 25% of the cases. Stones were made of struvite (35% of the cases), calcium-phosphate (25%) or calcium-oxalate (20%). The high prevalence of struvite stones reflects the importance of urinary tract infection a major cause of urolithiasis in that specific age group. Hypercalciuria was the most common urinary biochemical abnormality, found in more than 50% of the children. In the absence of a spontaneous passage of the stone, extra-corporeal shock wave lithotripsy represents an excellent therapeutic option. This article emphasizes the importance of stone analysis and extensive biochemical investigations in children with urolithiasis, in order to avoid recurrence and potential progression towards chronic renal failure.
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