Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biopharmaceuticals derived from genetically modified plants.

D A Goldstein1, J A Thomas

  • 1Monsanto Company A2NE, 800 N. Lindbergh Blvd, St Louis, MO 63167, USA. daniel.a.goldstein@monsanto.com

QJM : Monthly Journal of the Association of Physicians
|October 22, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhancing cost-effectiveness considerations in the adoption of new drugs in Hong Kong.

Hong Kong medical journal = Xianggang yi xue za zhi·2025
Same author

Patient-centered, self-funding dose optimization trials as a route to reduce toxicity, lower cost, and improve access to cancer therapy.

Annals of oncology : official journal of the European Society for Medical Oncology·2023
Same author

Improving access to immunotherapy in low- and middle-income countries.

Annals of oncology : official journal of the European Society for Medical Oncology·2022
Same author

Detection of Cross-Correlation between Gravitational Lensing and γ Rays.

Physical review letters·2020
Same author

Cosmological Constraints from Multiple Probes in the Dark Energy Survey.

Physical review letters·2019
Same author

Comparable outcomes following two or three cycles of high-dose chemotherapy and autologous stem cell transplantation for patients with relapsed/refractory germ cell tumors.

Bone marrow transplantation·2016
Same journal

Trends in mortality of people on dialysis in England and Wales over the last 15 years.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Familial pulmonary fibrosis due to pathogenic TERT variant presenting with a UIP-PPFE phenotype.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Corkscrew Oesophagus Due to Distal Oesophageal Spasm.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Correction to: Integrated care management for patients following acute stroke: a systematic review.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Methodological concerns regarding blinding and long term efficacy of fire needle therapy for plaque psoriasis.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Media framing of GLP-1/GIP therapies in Japan: Lessons for aging universal health coverage systems.

QJM : monthly journal of the Association of Physicians·2026
See all related articles

Plants are increasingly engineered to produce therapeutic proteins, addressing limitations in current biopharmaceutical production. This technology offers a promising, efficient, and scalable approach for developing new medicines.

Area of Science:

  • Biotechnology
  • Molecular Biology
  • Pharmacology

Background:

  • Modern biotechnology enables the use of plants for producing novel therapeutic agents.
  • There are nearly 500 biotechnology products approved or in development globally, highlighting production capacity limitations.
  • Efficient therapeutic protein production is crucial for meeting global demand.

Purpose of the Study:

  • To explore the potential of plants as a production system for biopharmaceuticals.
  • To discuss the selection of host plants and gene expression systems for efficient production.
  • To address safety and regulatory considerations for plant-based biopharmaceutical production.

Main Methods:

  • Genetic engineering of plants to express pharmacologically active proteins.

Related Experiment Videos

  • Selection of appropriate host plant species (food vs. non-food crops).
  • Evaluation of gene expression systems for optimal protein production.

    • Main Results:

    • Plants can be engineered to produce a wide range of therapeutic proteins, including antibodies, vaccines, and hormones.
    • Efficient production requires careful selection of host plants and expression systems.
    • Successful implementation necessitates addressing safety and regulatory frameworks.

    Conclusions:

    • Plant-based production of pharmaceuticals holds significant potential for the biopharmaceutical industry.
    • This approach offers an efficient and scalable method for producing various therapeutic agents.
    • Careful consideration of host selection, expression systems, safety, and regulation is vital for commercial viability.