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Updated: Aug 21, 2026

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
Published on: October 30, 2018
Comments on the Jayjock et al. paper
1Department of Pharmacology, Toxicology and Therapeutics, the University of Kansas, 66160-7417, USA. krozman@kumc.edu
Abstract:
Establishing hormesis as an evolution-based biological phenomenon requires a broad discussion of its implications for currently used risk paradigms. The Jayjock et al. papers provide an industrial hygienist's perspective and, as such, represent a valuable contribution to this discussion. Our comments outline a toxicologist's view on the limits and practicability of the Jayjock et al. suggestions. The arguments are primarily based on the shape of dose and time responses and associated variabilities and uncertainties.
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