Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone marrow pathology in AIDS.

Edenilson Eduardo Calore1, Paula Yurie Tanaka, Nilda Maria Perez

  • 1Emílio Ribas Institute of Infectology, Pathology Section, Av. Dr. Arnaldo 165, São Paulo 01246-902, Brazil. calore@uol.com.br

Pathology, Research and Practice
|October 23, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New proteasome inhibitors in the treatment of multiple myeloma.

Hematology, transfusion and cell therapy·2019
Same author

Epstein-Barr Viral Load is Associated to Response in AIDS-Related Lymphomas.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion·2014
Same author

Local control of human papillomavirus infection after anal condylomata acuminata eradication.

Revista do Colegio Brasileiro de Cirurgioes·2014
Same author

Assessment of labile plasma iron in patients who undergo hematopoietic stem cell transplantation.

Acta haematologica·2013
Same author

Thrombocytopenia in HIV-Infected Patients.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion·2013
Same author

Evaluation of Langerhans cells counts comparing HIV-positive and negative anal squamous cell-carcinoma patients.

Acta cirurgica brasileira·2012

Bone marrow biopsies in patients with Acquired Immunodeficiency Syndrome (AIDS) reveal frequent abnormalities. These findings highlight the importance of bone marrow examination for diagnosing infections and lymphomas in AIDS patients.

Area of Science:

  • Hematology
  • Infectious Diseases
  • Oncology

Background:

  • Bone marrow morphology often presents abnormalities in patients diagnosed with Acquired Immunodeficiency Syndrome (AIDS).
  • The Emílio Ribas Institute of Infectology, a key HIV reference center, served as the study location.

Purpose of the Study:

  • To review bone marrow biopsies from AIDS patients to identify the causes of cytopenias, secondary infections, and fever of unknown origin.
  • To determine the diagnostic utility of bone marrow biopsy in the management of complex cases in AIDS patients.

Main Methods:

  • Retrospective review of 97 bone marrow biopsies from AIDS patients conducted between 1998 and 2000.
  • Analysis of biopsy results for specific diagnoses, including fungal infections, mycobacterial infections, lymphomas, and inflammatory patterns.

Related Experiment Videos

Main Results:

  • Specific diagnoses were established in 33 cases.
  • Fungal infections (Histoplasma capsulatum, Cryptococcus neoformans, Candida albicans) were identified in 8 cases.
  • Acid-fast bacilli were present in 12 biopsies.
  • Lymphomatous infiltration (non-Hodgkin's and Hodgkin's lymphoma) was observed in 6 cases.
  • Necrotic changes, with or without granuloma formation, were noted in 12 cases.

Conclusions:

  • Bone marrow biopsy is a valuable diagnostic tool for identifying the etiology of cytopenias, secondary infections, and fever of undetermined origin in AIDS patients.
  • The procedure aids in the early detection and management of opportunistic infections and hematologic malignancies in this immunocompromised population.