Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postgastrectomy syndromes.

J C Eagon1, B W Miedema, K A Kelly

  • 1Department of Surgery, Mayo Medical School, Rochester, Minnesota.

The Surgical Clinics of North America
|April 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-omic analysis reveals brain-blood concordance and persistent neuroimmune reprogramming with stress and toxicant exposure in a mouse model of Gulf War Illness.

Brain, behavior, & immunity - health·2026
Same author

Early major complications after bariatric surgery in the USA, 2003-2014: a systematic review and meta-analysis.

Obesity reviews : an official journal of the International Association for the Study of Obesity·2017
Same author

Perioperative risk and complications of revisional bariatric surgery compared to primary Roux-en-Y gastric bypass.

Surgical endoscopy·2014
Same author

Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat.

Neuroscience·2010
Same author

Decrease in hepatic very-low-density lipoprotein-triglyceride secretion after weight loss is inversely associated with changes in circulating leptin.

Diabetes, obesity & metabolism·2010
Same author

Inflammasomes bridge signaling between pathogen identification and the immune response.

Drugs of today (Barcelona, Spain : 1998)·2009
Same journal

Social Determinants of Health, Health Disparities, and Surgical Equity.

The Surgical clinics of North America·2026
Same journal

Beyond the Scalpel's Reach.

The Surgical clinics of North America·2026
Same journal

Stepwise Solutions-Society.

The Surgical clinics of North America·2026
Same journal

Stepwise Solutions-Hospitals.

The Surgical clinics of North America·2026
Same journal

Stepwise Solutions for Providers.

The Surgical clinics of North America·2026
Same journal

Stepwise Solutions-Patients Social Determinants of Health, Health Disparities, and Surgical Equity.

The Surgical clinics of North America·2026
See all related articles

Postgastrectomy syndromes affect 20% of patients due to altered stomach motor functions after surgery. Treatment involves conservative measures, with surgery like Roux-en-Y gastrojejunostomy for persistent symptoms.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Digestive Physiology

Background:

  • Gastric surgery can lead to postgastrectomy syndromes in approximately 20% of patients.
  • These syndromes stem from operation-induced abnormalities in gastric motor functions, including reservoir, mechanical-digestive, and transport functions.
  • Vagal denervation and pyloric ablation/bypass are key contributors to these syndromes.

Purpose of the Study:

  • To elucidate the causes and mechanisms of postgastrectomy syndromes.
  • To emphasize the critical role of accurate syndrome diagnosis in treatment planning.
  • To review current and potential future treatment strategies for these conditions.

Main Methods:

  • Review of literature on postgastrectomy syndromes.

Related Experiment Videos

  • Discussion of diagnostic tools including endoscopy, contrast radiography, and scintigraphic gastric emptying studies.
  • Analysis of conservative and surgical treatment options.

    • Main Results:

    • Syndromes can manifest as rapid or slow gastric emptying and duodenal-gastric reflux.
    • Endoscopy is crucial for ruling out mechanical causes in slow emptying or reflux gastritis.
    • Conservative management (medical, dietary, behavioral) should be trialed for at least one year.

    Conclusions:

    • Accurate diagnosis is essential for effective treatment of postgastrectomy syndromes.
    • Conservative measures should be attempted first, followed by surgical interventions if necessary.
    • Surgical options like Roux-en-Y gastrojejunostomy and near-total gastrectomy offer solutions for specific syndromes, with emerging techniques showing future promise.