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Paediatric uveitis: a Sydney clinic experience
1The Children's Hospital at Westmead, Sydney, New South Wales, Australia. domitazar@student.usyd.edu.au
Insights
This study reviewed pediatric uveitis cases, finding idiopathic uveitis most common. Complications like cataracts and vision loss occurred, highlighting the need for careful management in pediatric ophthalmology.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Inflammatory Eye Diseases
Background:
- Uveitis in children presents unique diagnostic and management challenges.
- Understanding the epidemiology and etiology of pediatric uveitis is crucial for effective treatment strategies.
Purpose of the Study:
- To retrospectively review pediatric uveitis cases treated at The Children's Hospital at Westmead, Sydney.
- To compare findings with international uveitis studies, considering referral bias and etiological factors.
Main Methods:
- Retrospective review of medical records of pediatric uveitis patients.
- Data collection from 1989 to 2001, including patients from Camperdown and Westmead campuses.
Main Results:
- Forty pediatric patients (53 eyes) were analyzed, with a mean age of 6.7 years.
- Anterior uveitis was most common (66%), followed by panuveitis (15.1%). Idiopathic cases constituted 60%, with juvenile rheumatoid arthritis being the most frequent associated condition (17.5%).
- Complications included cataract (26.4%), band keratopathy (7.5%), macular scarring (5.7%), and glaucoma (7.5%). Visual acuity outcomes varied, with 15.1% having severe vision impairment (<6/60).
Conclusions:
- Pediatric uveitis cases at this center showed a high proportion of idiopathic disease and significant complications.
- Comparisons with international data suggest referral bias and etiological differences influence study outcomes.
- Further research is needed to elucidate specific risk factors and optimize management for pediatric uveitis.
Purpose:
The aim of this study was to retrospectively review uveitis cases at The Children's Hospital at Westmead, Sydney, since its inception in 1997 to 2001, including patients presenting at the Camperdown, Sydney, campus between 1989 and 1997 attending Westmead for further care. Comparison is made with international centres.
Methods:
Information was obtained from medical records.
Results:
Forty patients (53 eyes) presented, of whom 23 (57.5%) were female and 17 (42.5%) were male (mean age 6.7 years). Of 53 eyes, 35 (66%) had anterior uveitis, three (5.7%) intermediate uveitis, seven (13.2%) posterior uveitis and eight (15.1%) panuveitis. Twenty-seven (67.5%) patients had disease unilaterally and 13 (32.5%) bilaterally. Twenty-four (60%) cases were idiopathic. Seven (17.5%) cases were associated with juvenile rheumatoid arthritis, three (7.5%) with herpes zoster, two (5%) with herpes simplex, two (5%) with toxocara, one (2.5%) with toxoplasma, and one (2.5%) with ulcerative colitis. Complications included cataract in 14 (26.4%) eyes; band keratopathy in four (7.5%) eyes; macular scarring in three (5.7%) eyes; and glaucoma in four (7.5%) eyes. Last measured acuity was 6/6 for 19 (35.8%) eyes, < or =6/18 for 15 (28.3%) eyes and <6/60 for eight (15.1%) eyes.
Conclusions:
Despite small numbers, the comparisons of this study with some international studies, and its contrasts with other studies, are due to similarities and differences amongst these studies with respect to factors of referral bias, and the aetiological basis of disease.
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