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Updated: Aug 21, 2026
Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
[Study on the potentiation of bone marrow mesenchymal stem cells involved in sebaceous duct formation]
Li-jun Fang1, Xiao-bing Fu, Biao Cheng
1Department of Stomatology of the Second Affiliated Hospital of Chinese Medical University, Shenyang 110003, China. fuxb@vip.sina.com
Objective:
To investigate the feasibility of differentiation of bone marrow mesenchymal stem cells (MSCs) into skin appandence.
Methods:
Porcine MSCs were isolated from porcine marrow and grown in vitro. After labeling with BrdU, MSCs were engrafted to porcine skin. At 1, 2, 4 weeks after the transplantation, immunohistochemical examinations were carried out to detect the positive staining of BrdU and cytokeratin.
Results:
A few sebaceous duct cells, which expressed cytokeratin, were also BrdU positive, and these cells were considered may to be transplanted MSCs-derived cells.
Conclusion:
Porcine MSCs might have the potential to differentiated into sebaceous duct cells in skin.
