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Updated: Aug 21, 2026

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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
Published on: June 9, 2017
Hedgehog signaling: measuring ligand concentrations with receptor ratios
1Developmental Neurobiology, National Institute for Medical Research The Ridgeway, Mill Hill, London, NW7 1AA, UK.
Current Biology : CB
|October 23, 2004
Abstract
None:
How the binding of Hedgehog to its receptor, Patched, initiates signaling is poorly understood. A recent study suggests a mechanism by which the ratio of unliganded to liganded Patched determines the cellular response.

