[Prevention and management of complications in nephrotic syndrome]

Nephrotic syndrome is defined as the glomerular disease with massive proteinuria and hypoalbuminemia, and complications are numerous. Among these complications, saltwater retention, thromboembolism, hyperlipidemia, metabolic bone disease, infections are important for management of nephrotic syndrome. Recent advances in the understanding of alterations in the metabolism of circulating and somatic proteins associated with proteinuria and hypooncotic condition have led to new insights into the pathophysiologic processes associated with this syndrome. Therapeutic consideration should be paid not only for the treatment of primary diseases, but also for the prevention of these complications.