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Updated: Aug 21, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
Published on: October 31, 2025
Bilateral consolidation of the lungs in a preterm infant: an unusual central venous catheter complication
Maria Serenella Pignotti1, Antonio Messineo, Giuseppe Indolfi
1Department of Pediatrics, Neonatal Intensive Care Unit, Meyer Children's Hospital, University of Florence, Florence, Italy. m.pignotti@meyer.it
Abstract:
We describe a case of bilateral parenchymal consolidation with sudden respiratory distress in a preterm baby as a complication of peripherally inserted central catheter (PICC) dislocation. The X-rays showed bilateral pulmonary consolidation with the catheter tip initially located in the right, and later in the left pulmonary artery. The catheter was withdrawn. As soon as the catheter was repositioned all clinical signs and symptoms disappeared. Neonatologists should consider the possibility of dramatic respiratory distress deriving from PICC dislocation. Careful tip catheter placement and conscientious monitoring may reduce morbidity.
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