Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Patch testing with metalworking fluids from the patient's workplace.

Johannes Geier1, Wolfgang Uter, Holger Lessmann

  • 1Information Network of Department of Dermatology, University of Göttingen, Göttingen, Germany. jgeier@ivdk.org

Contact Dermatitis
|October 27, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

S2k guideline occupational skin products: skin protection creams, skin cleansing and skin care products.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same author

Epidemiology of patch tested patients with permanent tattoos-A comparative analysis of 9693 IVDK patients (2020-2022).

Contact dermatitis·2024
Same author

Associations between tobacco smoking status and patch test results-A cross-sectional pilot study from the Information Network of Departments of Dermatology (IVDK).

Contact dermatitis·2024
Same author

Declining frequency of sensitization to fragrance mixes I and II: IVDK-data of the years 2012-2021.

Contact dermatitis·2023
Same author

Contact allergies to dental materials in patients.

The British journal of dermatology·2023
Same author

Contact allergy to ingredients of hair cosmetics in female hairdressers and female consumers-An update based on IVDK data 2013-2020.

Contact dermatitis·2023
Same journal

Contact Allergy and Allergic Contact Dermatitis From Propylene Glycol and Related Glycols: Cosmetic Skin Sensitisers After All?

Contact dermatitis·2026
Same journal

Acrylate Copolymers/Crosspolymers in Sunscreens: Minimally Allergenic, Without Evidence of Need for Avoidance by (Meth)Acrylate-Sensitized Individuals.

Contact dermatitis·2026
Same journal

AI-Assisted Automated Two-Stage Patch Test Interpretation System Using Vision Transformer.

Contact dermatitis·2026
Same journal

Use of Tralokinumab in a Hairdresser With Severe Chronic Hand Eczema and Occupational Allergic Contact Dermatitis.

Contact dermatitis·2026
Same journal

Occupational Allergic Contact Dermatitis Caused by Cyclohexyl Diethanolamine in a Metalworking Fluid.

Contact dermatitis·2026
Same journal

Fragrance and Preservative Contact Allergens in Cosmetic and Household Cleaning Products in Turkey: Variation by Target Population, Product Type and Manufacturing Origin.

Contact dermatitis·2026
See all related articles

Patch testing with workplace metalworking fluids (MWF) is crucial for diagnosing occupational contact dermatitis. Testing at workplace concentration is most effective, while lower dilutions may miss true allergies.

Area of Science:

  • Dermatology
  • Occupational Health
  • Toxicology

Background:

  • Metalworking fluids (MWF) contain diverse chemicals, increasing the risk of overlooked contact sensitizations.
  • Standardized MWF test series may not cover all components, necessitating workplace-specific testing.
  • Varied recommendations exist for performing patch tests with MWF.

Purpose of the Study:

  • To retrospectively analyze patch test data for metalworkers suspected of occupational contact dermatitis due to MWF.
  • To evaluate the effectiveness of different dilution series for patch testing MWF.
  • To provide recommendations for optimizing MWF patch testing procedures.

Main Methods:

  • Retrospective analysis of patch test data from 1992-2003 involving 141 metalworkers.

Related Experiment Videos

  • 829 patch tests were performed using 306 MWF samples.
  • Water-based MWF (wb MWF) were tested at workplace concentration (pure), 10% aq., 1% aq., 50% aq. Neat oils were tested pure or diluted.

    • Main Results:

    • 27 patients showed positive reactions to wb MWF.
    • Testing wb MWF at workplace concentration yielded a 16.1% positive reaction rate.
    • No reactions were observed with neat oils, even when diluted.

    Conclusions:

    • Patch testing with MWF at workplace concentration is vital for diagnosing true contact allergy.
    • Lower concentrations of MWF may lead to missed diagnoses.
    • Breakdown testing and full ingredient disclosure of MWF are recommended for improved diagnostics. A center for occupational contact allergy information is proposed.