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Related Experiment Videos

[Intravenous morphine titration].

F Aubrun1, N Valade, B Riou

  • 1Département d'anesthésie-réanimation chirurgicale, groupe hospitalier Pitié-Salpétrière, assistance publique-hôpitaux de Paris, université Pierre-et-Marie-Curie, 47-83, boulevard de l'Hôpital, 75651 Paris 13, France. frederic.aubrun@psl.ap-hop-paris.fr

Annales Francaises D'Anesthesie Et De Reanimation
|October 27, 2004
PubMed
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Intravenous morphine titration is a simple method for effective pain relief, especially post-surgery. This technique manages morphine side effects by administering doses until pain subsides, considering individual patient needs.

Area of Science:

  • Pharmacology
  • Pain Management
  • Anesthesiology

Context:

  • Intravenous (i.v.) morphine titration is a widely adopted analgesic strategy.
  • Its application spans prehospital care, emergency departments, post-anesthesia care units (PACU), intensive care units (ICU), and oncology.
  • Significant inter-patient variability exists in morphine requirements.

Purpose:

  • To outline the principles of intravenous morphine titration.
  • To synthesize current knowledge from experimental and clinical studies.
  • To provide evidence-based recommendations for clinical practice across various care settings.

Summary:

  • Intravenous morphine titration involves administering morphine boluses to achieve pain relief while minimizing dose-dependent side effects.

Related Experiment Videos

  • In the PACU, titration every five minutes with 2-3 mg boluses is effective for adults with a Visual Analogue Scale (VAS) > 30 mm.
  • Titration continues until pain relief (VAS ≤ 30 mm), acceptable sedation (Ramsay score > 1), or severe side effects are managed.

    • Impact:

    • Facilitates rapid and efficient pain management, particularly in the postoperative period.
    • Offers a practical approach to titrate analgesia based on individual patient response.
    • Aims to optimize pain control while mitigating risks associated with morphine administration.