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Atypical MR imaging perfusion in developmental venous anomalies
Daniel L A Camacho1, J Keith Smith, John D Grimme
1Department of Radiology, University of North Carolina, Chapel Hill, NC 27599, USA.
AJNR. American Journal of Neuroradiology
|October 27, 2004
Summary
Developmental venous anomalies (DVAs) are common brain vascular variants. Perfusion MRI in asymptomatic DVAs shows altered parameters, not indicating serious conditions like tumors or stroke.
Area of Science:
- Neuroimaging
- Cerebrovascular diseases
- Radiology
Background:
- Developmental venous anomalies (DVAs) represent common variations in cerebral venous drainage.
- DVAs are frequently discovered incidentally during contrast-enhanced Magnetic Resonance (MR) imaging.
- Understanding DVA imaging characteristics is crucial for accurate diagnosis.
Observation:
- This study examined four cases of asymptomatic DVAs.
- Perfusion MR imaging was utilized to assess hemodynamic parameters.
- Key parameters evaluated included cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT), and time to peak (TTP).
Findings:
- Asymptomatic DVAs exhibited increased CBF and CBV.
- Elevated MTT and TTP were also observed in these DVAs.
- These perfusion changes are associated with uncomplicated DVAs.
Implications:
- Altered perfusion MR imaging parameters can occur in DVAs without underlying pathology.
- Findings suggest that these perfusion changes do not necessarily indicate a hypervascular tumor or stroke.
- This research aids in differentiating DVA imaging findings from more severe neurological conditions.