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Primary fibrinogenolysis complicating second trimester placental separation
E Anteby1, A Milwidsky, R Goshen
1Department of Obstetrics and Gynecology, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel.
Archives of Gynecology and Obstetrics
|January 1, 1992
Summary
This case study details severe bleeding during second trimester placental separation. Primary fibrinogenolysis is the suspected cause of the patient
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Reproductive Medicine
Background:
- Second-trimester placental separation is a rare but serious obstetric emergency.
- Coagulopathy can significantly complicate management and increase maternal morbidity.
Observation:
- A case of severe bleeding during second-trimester placental separation is presented.
- The patient exhibited a severe bleeding diathesis.
Findings:
- Primary fibrinogenolysis is proposed as the underlying cause of the observed coagulopathy.
- This suggests a specific mechanism for the bleeding disorder in this context.
Implications:
- Understanding the pathophysiology of coagulopathy in placental separation is crucial for management.
- Early recognition and treatment of primary fibrinogenolysis may improve outcomes in similar obstetric emergencies.