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Related Experiment Videos

Late onset hyperekplexia.

Sophie Hamelin1, Pascale Rohr, Philippe Kahane

  • 1Epilepsy Unit, CHU Grenoble, France.

Epileptic Disorders : International Epilepsy Journal with Videotape
|October 27, 2004
PubMed
Summary
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An 86-year-old woman experienced sudden mobility loss due to myoclonus. Diagnosis of late-onset hyperekplexia was confirmed, and symptoms improved with clonazepam.

Area of Science:

  • Neurology
  • Clinical Case Study

Background:

  • A case study involving an 86-year-old female patient presenting with sudden inability to stand and walk.
  • The patient exhibited jerky movements suggestive of myoclonus, triggered by various stimuli.

Observation:

  • Both unexpected and expected stimuli (audiogenic, tactile, visual) elicited myoclonic jerks.
  • Electrophysiological studies (EEG-EMG) revealed a consistent patterned motor response to stimulation, including eye blinking, head flexion, arm abduction, trunk movement, and knee bending.

Findings:

  • Absence of significant past medical history, biological abnormalities, or neurological deficits on CT brain imaging.
  • Clinical presentation and electrophysiological findings supported a diagnosis of late-onset hyperekplexia.

Implications:

Related Experiment Videos

  • Low-dose clonazepam effectively reduced the clinical symptoms of hyperekplexia.
  • Highlights the importance of considering late-onset hyperekplexia in elderly patients with unexplained myoclonus and gait disturbances.