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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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An intramolecular ionic hydrogen bond stabilizes a cis amide bond rotamer of a ring-opened rapamycin-degradation

Casey Chun Zhou1, Kent D Stewart, Madhup K Dhaon

  • 1D-R418, Structural Chemistry, Global Pharmaceutical Research and Development, Abbott Laboratories, North Chicago, IL 60064-4000, USA. chun.zhou@abbott.com

Magnetic Resonance in Chemistry : MRC
|October 27, 2004
PubMed

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