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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

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Related Experiment Video

Updated: Jun 19, 2026

Using In Vivo and Tissue and Cell Explant Approaches to Study the Morphogenesis and Pathogenesis of the Embryonic and Perinatal Aorta
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[Endothelin gene-manipulated animals]

Takahiro Sato1, Hiroki Kurihara

  • 1Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|October 28, 2004
PubMed
Summary

No abstract available in PubMed .

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