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Infliximab for the treatment of posterior uveitis with retinal neovascularization in Behçet disease
F Giansanti1, M L Barbera, G Virgili
1Eye Clinic, Department of Oto-Neuro-Ophthalmological Surgical Sciences, University of Firenze, Firenze--Italy. fabriziogiansanti@interfree.it
Purpose:
To report a case of posterior uveitis with retinal neovascularization in a patient with Behçet disease treated with infliximab.
Methods:
A 50-year-old man with a history of recurrent relapses of ocular inflammation despite immunosuppressive therapy developed retinal neovascularization near the optic disk. The patient was treated with infliximab and followed up for 12 months.
Results:
Retinal neovascularization regressed 8 months after the first anti-tumor necrosis factor (TNF) treatment and with six infusions of infliximab. The ocular inflammation resolved almost completely.
Conclusions:
The result suggests that anti-TNF therapy may be effective in the treatment of retinal neovascularization caused by panuveitis in Behçet disease.
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