Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extractor for ESI quadrupole TOF tandem MS data enabled for high throughput batch processing.

Andreas M Boehm1, Robert P Galvin, Albert Sickmann

  • 1Protein Mass Spectrometry and Functional Proteomics Group, Rudolf-Virchow-Center for Experimental Biomedicine, Universitaet Wuerzburg, Versbacher Strasse 9, D-97078 Wuerzburg, Germany. andreas.boehm@virchow.uni-wuerzburg.de

BMC Bioinformatics
|October 28, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Active zone plasticity couples sleep need to presynaptic hypophosphorylation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Loss of cardiomyocyte AKT signaling causes deterioration of lipid metabolism and cellular atrophy.

Metabolism: clinical and experimental·2026
Same author

Oxygen-dependent modulation of the human complement system during acute normobaric hypoxia: a translational plasma proteomics study.

Clinical and experimental medicine·2026
Same author

Formation of tight junction-like structures of zonula occludens 2 in platelet-platelet interaction.

Research and practice in thrombosis and haemostasis·2026
Same author

Cardiac mitochondrial proteome of lean, healthy Ossabaw minipigs with predisposition to metabolic syndrome versus that of Göttingen minipigs.

American journal of physiology. Heart and circulatory physiology·2026
Same journal

OpenIMC: an open-source platform for analyzing single-cell and spatial proteomics by imaging mass cytometry.

BMC bioinformatics·2026
Same journal

NAP: an open source pipeline for cross-domain microbiome profiling using Nanopore sequencing-derived amplicon data.

BMC bioinformatics·2026
Same journal

SurvGME: an R package for survival analysis with graphical and measurement error models.

BMC bioinformatics·2026
Same journal

SimMapNet: a Bayesian framework for gene regulatory network inference using gene ontology similarities as external hint.

BMC bioinformatics·2026
Same journal

Dual channel drug-drug interactions extraction based on cross attention.

BMC bioinformatics·2026
Same journal

FeSseqdb: a curated sequence-level database and interpretable machine learning framework for identifying iron-sulfur proteins.

BMC bioinformatics·2026
See all related articles

wiff2dta is a new tool that efficiently converts mass spectrometry data from Applied Biosystems instruments. This proteomics software offers faster processing speeds and seamless integration into automated workflows.

Area of Science:

  • Proteomics
  • Mass Spectrometry Data Analysis

Background:

  • Mass spectrometry generates large datasets requiring real-time processing for identification algorithms.
  • Efficient data handling is crucial for automated proteomics environments.

Purpose of the Study:

  • Introduce wiff2dta, a novel tool for converting MS/MS data.
  • Facilitate real-time data processing for proteomics identification algorithms.

Main Methods:

  • Developed wiff2dta to process MS/MS data from Applied Biosystems QStar and QTrap series instruments.
  • Evaluated wiff2dta's performance against standard data conversion tools.

Main Results:

  • wiff2dta demonstrates superior speed, exceeding standard tools by at least 10% in spectrum data extraction.

Related Experiment Videos

  • The tool supports batch processing and integrates effectively into high-throughput environments.

    • Conclusions:

    • wiff2dta functions as a standalone application or command-line tool for automation.
    • Offers enhanced efficiency compared to existing state-of-the-art proteomics data processing tools.