Chemical composition and antimicrobial activity of the essential oil of Cordiaverbenacea D.C

Cordiaverbenacea D.C. (Boraginaceae) is found along the coastal regions of Brazil, from the Amazon basin to the southernmost state of Rio Grande do Sul. The aerial parts of this plant have been used in folk medicine since colonial times for their anti-rheumatic, anti-inflammatory, analgesic and healing properties. The objectives of this study were: the extraction of the essential oil of the aerial parts of this species and quantification of the yield thereof; the identification and quantification of the principal components of the essential oil; and the determination of its antimicrobial activity by plate diffusion method. The yield of essential oil was 0.19% (v/w) in relation to the fresh flowering aerial parts and 0.23% (v/w) of the leaves. The main constituents of the essential oil, identified by gas chromatography/mass spectrometry (GC/MS), were alpha-pinene (29.69%), trans-caryophyllene (25.27%) and aloaromadendrene (9.99%). The Gram-positive bacteria and yeast tested were sensitive to the essential oil of Cordiaverbenacea D.C., but most of the Gram-negative bacteria were resistant.