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Updated: Aug 21, 2026
Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Seminal fluid enhances replication of human T-cell leukemia virus type 1: implications for sexual transmission
Masako Moriuchi1, Hiroyuki Moriuchi
1Department of Pediatrics, Nagasaki University Hospital, Nagasaki 852-8501, Japan.
Abstract:
Seminal fluid enhanced human T-cell leukemia virus type 1 (HTLV-1) infection by transactivating the HTLV-1 long terminal repeat promoter, which is chromosomally integrated in a cell-type-dependent manner. Our data may indicate a potential role for seminal fluid in the sexual transmission of HTLV-1 and imply complex features of regulation of HTLV-1 expression.
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