Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Conceptualizing human variation.

S O Y Keita1, R A Kittles, C D M Royal

  • 1National Human Genome Center, College of Medicine, Howard University, Washington, DC 20060, USA.

Nature Genetics
|October 28, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The need for an integrated approach for chronic disease research and care in Africa.

Global health, epidemiology and genomics·2018
Same author

H3Africa multi-centre study of the prevalence and environmental and genetic determinants of type 2 diabetes in sub-Saharan Africa: study protocol.

Global health, epidemiology and genomics·2017
Same author

Pharmacogenomic implications of the evolutionary history of infectious diseases in Africa.

The pharmacogenomics journal·2016
Same author

Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men.

Epigenetics·2015
Same author

Ethnicity-specific pharmacogenetics: the case of warfarin in African Americans.

The pharmacogenomics journal·2013
Same author

Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia.

Prostate cancer and prostatic diseases·2013
Same journal

Mutations in splicing factor gene U2AF1 rescue defective oncogene splicing in KRAS-mutant cancers.

Nature genetics·2026
Same journal

Assessing the effect of immune surveillance on clonal expansions in the blood.

Nature genetics·2026
Same journal

Improved heritability partitioning and enrichment analyses using summary statistics with graphREML.

Nature genetics·2026
Same journal

U2AF1 mutations rescue deleterious exon skipping induced by KRAS mutations.

Nature genetics·2026
Same journal

Lineage tracing from cellular heritage to disease destiny.

Nature genetics·2026
Same journal

Multiomics analysis of primary metabolism reveals the genetic basis of nitrogen partitioning modulated by ZmAVT1A-1 in maize.

Nature genetics·2026
See all related articles

The study examines the scientific validity of "race" in explaining human biological and sociocultural variation. It questions if current racial classifications accurately reflect genetic and demographic group differences, advocating for a more nuanced approach to human variation research.

Area of Science:

  • Anthropology
  • Genetics
  • Sociology
  • Public Health

Background:

  • Human populations exhibit biological and sociocultural variations across different demographic groups.
  • The concept of 'race' is frequently used to explain observed differences in disease incidence and prevalence.
  • Existing 'racial' classifications are debated for their scientific accuracy and utility in understanding human variation.

Purpose of the Study:

  • To explore the relationship between biological and sociocultural variation in extant humans.
  • To critically evaluate the term 'race' and 'racial' classification schemas.
  • To investigate the connection between 'race', genetics, and societal demographic groups.

Main Methods:

  • Review and analysis of existing data on human biological and sociocultural variation.

Related Experiment Videos

  • Exploration of the meaning and application of the term 'race' in scientific discourse.
  • Examination of the relationship between genetic data and demographic group categorizations.

    • Main Results:

    • The study questions the scientific validity of 'race' as a biological construct for categorizing humans.
    • Observed differences between demographic groups are complex and not solely explained by traditional 'racial' categories.
    • Current approaches may oversimplify the intricate patterns of human variation.

    Conclusions:

    • A more scientifically robust and useful framework is needed to understand human biological variation.
    • Rethinking the application of 'race' can lead to improved research designs.
    • This approach can better inform public policy related to health and social disparities.