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Updated: Aug 21, 2026

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point
Published on: June 28, 2024
Isolated third and fourth ventricles associated with neurosarcoidosis successfully treated by neuroendoscopy--case
Hideo Hamada1, Nakamasa Hayashi, Masanori Kurimoto
1Department of Neurosurgery, Toyama Medical and Pharmaceutical University, Toyama, Japan. hideo@ms.toyama-mpu.ac.jp
Abstract:
A 48-year-old woman presented with a unique case of isolated third and fourth ventricles associated with neurosarcoidosis, manifesting as upward gaze palsy. She had a past history of surgery for intracranial sarcoid granuloma 10 years previously and placement of a ventriculoperitoneal shunt 3 years later. Magnetic resonance imaging revealed isolated third and fourth ventricles. Endoscopic plasty of the right foramen of Monro, fenestration of the septum pellucidum, and revision of the ventriculoperitoneal shunt were performed. Postoperatively the size of the third and fourth ventricles was reduced, and the upward gaze palsy resolved. Endoscopic treatment is less invasive and effective for the treatment of multiple septum formation in the ventricular system.
