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Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)
Published on: December 19, 2019
Management of health and safety in carcinogenesis bioassay programs
1Tracor Jitco, Inc., Rockville, MD 20852, USA.
Abstract:
Working with proven or potential chemical carcinogens on a routine basis presents complex safety and health problems. These are compounded when a number of laboratories under separate managements are brought together under a centrally supervised study. This paper presents the types of hazards encountered in such a program and describes the approach used in its overall management. Significant improvements in worker health and safety are being achieved through a centrally-coordinated system of self-assessments, hazard surveys, facility monitoring, and chemical control evaluations.
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