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Central obesity and elevated liver enzymes.

Gregory M Lam1, Sohrab Mobarhan

  • 1Department of Internal Medicine, Loyola University Medical Center, Maywood, Illinois 60153, USA. glam@lumc.edu

Nutrition Reviews
|October 29, 2004
PubMed
Summary

Nonalcoholic fatty liver disease (NAFLD) is linked to obesity. A study found central adiposity, particularly visceral fat, is significantly associated with higher liver enzymes, indicating adverse health effects.

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Area of Science:

  • Hepatology
  • Metabolic Syndrome
  • Public Health

Background:

  • Nonalcoholic fatty liver disease (NAFLD) is a prevalent condition often linked to the global obesity epidemic.
  • Central adiposity is increasingly recognized as a risk factor for metabolic dysfunction.

Purpose of the Study:

  • To investigate the association between central adiposity and liver enzyme levels.
  • To explore the specific role of visceral adiposity in liver health.

Main Methods:

  • A large, population-based investigation was conducted.
  • Statistical analyses were used to determine the significance of the association between adiposity measures and liver enzymes.

Main Results:

  • A statistically significant association was found between central adiposity and elevated liver enzymes.
  • Visceral adiposity showed a specific link to adverse health effects.

Conclusions:

  • Central adiposity is a significant indicator of elevated liver enzymes.
  • Findings support the link between visceral fat accumulation and negative health outcomes, particularly in NAFLD.

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