Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Trypanosome-induced hypothyroidism in cattle.

G Abebe1, R M Eley

  • 1International Laboratory for Research on Animal Diseases (ILRAD), Nairobi, Kenya.

The British Veterinary Journal
|January 1, 1992
PubMed
Summary

Trypanosomiasis infection in Boran cattle significantly reduces plasma thyroxine (T4) levels. This study investigated the impact of Trypanosoma congolense on thyroid function in cattle, revealing a notable decrease in T4 concentrations in infected animals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and mortality rate of sepsis among adults admitted to hospitals in sub-Saharan Africa: a systematic review and meta-analysis.

The Journal of hospital infection·2023
Same author

Genomic Regions and Candidate Genes Associated with Milk Production Traits in Holstein and Its Crossbred Cattle: A Review.

International journal of genomics·2023
Same author

Diagnostic value of Xpert MTB/RIF assay on pleural tissue obtained via closed pleural biopsy among persons with presumptive tuberculous pleuritis.

African journal of thoracic and critical care medicine·2021
Same author

Reproduction in the vervet monkey (Cercopithecus aethiops): II. Annual menstrual patterns and seasonality.

American journal of primatology·2020
Same author

Reproduction in the vervet monkey (Cercopithecus aethiops): I. Testicular volume, testosterone, and seasonality.

American journal of primatology·2020
Same author

Reproduction in the vervet monkey (Cercopithecus aethiops): III. The menstrual cycle.

American journal of primatology·2020

Area of Science:

  • Veterinary Medicine
  • Parasitology
  • Endocrinology

Background:

  • Trypanosomiasis is a significant disease affecting livestock in many regions.
  • Thyroid hormones play a crucial role in metabolic regulation and overall health.
  • The impact of trypanosomiasis on thyroid function in cattle requires further elucidation.

Purpose of the Study:

  • To investigate the effect of Trypanosoma congolense infection on thyroid gland function in Boran cattle.
  • To quantify changes in plasma thyroxine (T4) concentrations during trypanosomiasis.

Main Methods:

  • Experimental infection of Boran cattle with Trypanosoma congolense IL 1180.
  • Weekly measurement of plasma thyroxine (T4) using 125I-radioimmunoassay.
  • Comparison of T4 levels between infected and uninfected control cattle.

Main Results:

  • Trypanosoma congolense infection led to a significant decline in plasma T4 concentration.
  • Infected Boran cattle exhibited lower T4 levels compared to control animals.
  • The data indicates a clear impact of trypanosomiasis on thyroid hormone levels.

Conclusions:

  • Trypanosomiasis caused by T. congolense significantly affects thyroid function in Boran cattle.
  • Plasma T4 levels are a potential indicator of the disease's impact on thyroid health.
  • Further research may explore the mechanisms behind this T4 suppression.

Related Experiment Videos