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Updated: Jun 28, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Outcomes of congenital heart disease: a review
1University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Insights
Congenital heart disease (CHD) affects one million Americans, causing physical, behavioral, and psychiatric issues. More research is needed on long-term outcomes for patients treated with modern medical advancements.
Area of Science:
- Cardiology
- Pediatric Medicine
- Public Health
Background:
- Congenital heart disease (CHD) impacts approximately one million Americans.
- Improved survival rates highlight the multifaceted effects of CHD on patients' lives.
- Existing research indicates challenges in physical growth, motor function, and exercise tolerance.
Purpose of the Study:
- To review the current understanding of the impact of congenital heart disease (CHD) on affected individuals.
- To identify areas where more research is needed regarding CHD outcomes.
- To examine the long-term effects of CHD, particularly in patients managed with contemporary medical technologies.
Main Methods:
- Literature review of studies on congenital heart disease (CHD) outcomes.
- Analysis of reported physical, behavioral, and psychiatric effects in children and adults with CHD.
- Synthesis of data concerning quality of life (QOL) in CHD populations.
Main Results:
- Patients with CHD frequently experience issues with physical growth and gross motor development.
- Adults with CHD, even those with minor defects, often exhibit reduced exercise tolerance.
- Adolescents and young adults with CHD show increased prevalence of behavioral and psychiatric conditions, including depression and anxiety disorders.
Conclusions:
- Congenital heart disease (CHD) presents a complex spectrum of lifelong challenges.
- Current data on quality of life (QOL) in CHD patients are conflicting and require further investigation.
- There is a critical need for comprehensive outcome research on individuals diagnosed, managed, and repaired using modern CHD treatment strategies.
Abstract:
One million Americans are affected by congenital heart disease (CHD) (American Heart Association [AHA], 2003). As survival has improved, evidence has accumulated that CHD touches many aspects of the lives of those affected. Children and adults report difficulties with physical growth and/or stature. Gross motor abnormalities are common in both groups, and significantly reduced exercise tolerance is reported in adults with CHD, including those with minor defects. Behavioral and psychiatric abnormalities are reported in adolescents and young adults, including a significant incidence of depression and anxiety disorders. The data are conflicting regarding quality of life (QOL) in children and adults with CHD. More research is needed examining outcomes, particularly outcomes of those diagnosed, managed, and repaired using modern technology.
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