Related Experiment Video
Updated: Jul 10, 2026

Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
A generalized estimating equations approach to mixed-effects ordinal probit models
Timothy R Johnson1, Jee-Seon Kim
1Department of Statistics, University of Idaho, Moscow, ID 83844-1104, USA. trjohns@uidaho.edu
Abstract:
Clustered ordinal responses, which are commonplace in behavioural and educational research, are often analysed using mixed-effects ordinal probit models. Likelihood-based inference for these models can be computationally burdensome, and may compromise the consistency of estimators if the model is misspecified. We propose an alternative inferential approach based on generalized estimating equations. We show that systems of estimating equations can be specified for mixed-effects ordinal probit models that avoid the potentially heavy computational demands of maximum likelihood estimation, and can also provide inferences that are robust with respect to some forms of model misspecification--particularly serial effects in longitudinal data.
Related Concept Videos
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation
On...
Mechanistic Models: Compartment Models in Individual and Population Analysis
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Pharmacodynamic Models: Additive and Proportional Drug Effect Model
Friedman Two-way Analysis of Variance by Ranks
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...

