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Monochorionic triplets after single embryo transfer.

Francisco Rísquez¹, Mónica Gil, Gustavo D'Ommar

¹Clínica de Fertilidad, Centro Médico Docente La Trinidad, Caracas, Venezuela. risquezf@cantv.net

Reproductive Biomedicine Online

|October 30, 2004

Summary

This case study highlights a rare monochorionic tri-amniotic pregnancy after single embryo transfer during in vitro fertilization (IVF). Further research is needed to identify predictive factors for monozygotic twinning to prevent multiple pregnancies.

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Area of Science:

Reproductive Medicine
Embryology
Maternal-Fetal Medicine

Background:

Assisted reproductive technologies like intracytoplasmic sperm injection (ICSI) and assisted hatching are common.
Single embryo transfer is the standard practice to minimize multiple gestations.
Monozygotic twinning, though rare, can occur spontaneously or after IVF.

Observation:

A 40-year-old patient underwent ICSI and assisted hatching, with a single embryo transfer.
Ultrasound revealed a monochorionic tri-amniotic pregnancy, a rare form of multiple gestation.
The patient's case presented several potential etiological factors for monozygotic triplet pregnancy.

Findings:

The occurrence of a monochorionic tri-amniotic pregnancy following single embryo transfer is exceptionally rare.

Related Experiment Videos

The case suggests that certain factors associated with IVF procedures may contribute to monozygotic twinning.

Identifying these factors is crucial for understanding the etiology of such events.

Implications:

There is a need for definitive predictive factors to identify IVF patients at risk for monozygotic multiple pregnancies.
Further research should focus on the mechanisms leading to monozygotic twinning after assisted reproductive technologies.
Establishing clear predictive markers will enhance the safety and efficacy of IVF treatments, aiming to prevent iatrogenic multiple gestations.