Related Experiment Video
Updated: Aug 21, 2026
Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
Published on: March 14, 2013
Continuous measurement of cerebral blood volume and oxygenation during rewarming of neonates
G Naulaers1, V Cossey, G Morren
1Department of Paediatrics, University Hospital Leuven, ESAT-SCD (SISTA), Leuven, Belgium. gunnar.naulaers@uz.kuleuven.ac.be
Aim:
To investigate the effect of rewarming in preterm infants presenting with hypothermia at admission.
Methods:
The tissue oxygenation index (TOI), changes in cerebral blood volume (DeltaCBV) and changes in intravascular oxygenation (DeltaHbD) were measured in eight preterm infants, presenting with a temperature less than 35 degrees C at admission.
Results:
A significant increase in HbD and TOI was seen in four patients (group A), while a significant increase in CBV and a decrease in HbD was seen in four other patients (group B). Retrospective analysis showed that group A had important signs of peripartal asphyxia.
Conclusion:
While infants with peripartal asphyxia showed an important increase in oxygenation during rewarming, no significant changes were seen in the non-asphyxiated infants.
