Related Experiment Video
Updated: Aug 21, 2026

Mapping Dysfunctional Protein-Protein Interactions in Disease
Published on: October 24, 2025
hp-DPI: Helicobacter pylori database of protein interactomes--embracing experimental and inferred interactions
Chung-Yen Lin1, Chia-Ling Chen, Chi-Shiang Cho
1Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw
Abstract:
We implemented a statistical model into our protein interaction database for validation of two-hybrid assays of Helicobacter pylori, and prediction of putative protein interactions not yet discovered experimentally. To present the enormous amount of experimental and inferred protein interaction networking maps, the H.pylori Database of Protein Interactomes (hp-DPI) is developed with a succinct yet comprehensive visualization tool integrated with annotation from Genbank, GO, and KEGG. hp-DPI is first built with, but not limited to, H.pylori protein interactions and is expected to naturally include other organisms' protein interacting relationships in the future.
More Related Videos
13:56A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
Published on: July 18, 2013
10:44One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode
Published on: June 18, 2016
Related Concept Videos
Protein-protein Interfaces
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Gastritis II: Pathophysiology