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Updated: Aug 21, 2026

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection
Published on: May 2, 2011
Research and development of new vaccines against infectious diseases
Marie Paule Kieny1, Jean-Louis Excler, Marc Girard
1Initiative for Vaccine Research, World Health Organization, Avenue Appia 20, CH1211-Genève 27, Switzerland. kienym@who.int
Insights
Vaccine access for all children can significantly reduce infectious disease deaths. Developing new vaccines and ensuring equitable distribution are crucial for global child health.
Area of Science:
- Global Health
- Vaccinology
- Pediatric Infectious Diseases
Background:
- Infectious diseases cause a quarter of global deaths, disproportionately affecting children under five.
- Current vaccination strategies are insufficient to reach all populations, particularly in resource-limited settings.
Purpose of the Study:
- To highlight the critical need for universal access to existing basic vaccines for children.
- To advocate for the development of novel vaccines against prevalent infectious agents.
- To emphasize the necessity of global collaboration for vaccine accessibility.
Main Methods:
- This study is a review and synthesis of current global health challenges related to infectious diseases and vaccination.
- It analyzes the impact of vaccine accessibility on child mortality rates.
- It discusses the potential of new vaccine technologies and public-private partnerships.
Main Results:
- Equitable vaccine distribution can substantially decrease child mortality from infectious diseases.
- Development of new vaccines is essential for infections lacking preventive measures.
- Collaborative efforts are vital for rapid vaccine deployment.
Conclusions:
- Achieving universal vaccine access for children is paramount to reducing global mortality.
- Continued innovation in vaccine development and equitable distribution strategies are urgently required.
- Public, private, and philanthropic sectors must unite to accelerate vaccine availability for vulnerable populations.
Abstract:
Infectious diseases are responsible for approximately 25% of global mortality, especially in children aged younger than 5 years. Much of the burden of infectious diseases could be alleviated if appropriate mechanisms could be put in place to ensure access for all children to basic vaccines, regardless of geographical location or economic status. In addition, new safe and effective vaccines should be developed for a variety of infections against which no effective preventive intervention measure is either available or practical. The public, private, and philanthropic sectors need to join forces to ensure that these new or improved vaccines are fully developed and become accessible to the populations in need as quickly as possible.
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