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Histochemical study of mast cells from the thymus of mice receiving ACTH1-24
1Laboratory of the Department for Medical Biology, Chuvash State University, Cheboksary. nema@chuvsu.ru
Abstract:
Synthetic ACTH1-24 analogue administered in a daily dose of 0.01 mg/kg decreased the number and size of mast cells and increased intracellular serotonin concentration. ACTH1-24 induced degranulation of young mast cells and release of undersulfated heparin. Correlation analysis showed that hormonal imbalance produced by ACTH1-24 was accompanied by redistribution of bioamines.
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