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Risk factors for cholelithiasis in pregnancy
Glenda Lindseth1, Marilyn Yellow Bird-Baker
1University of North Dakota, Box 9025, Grand Forks, ND 58201, USA.
Research in Nursing & Health
|October 30, 2004
Summary
Native American pregnant women experienced higher rates of symptomatic gallstones. Higher Body Mass Index (BMI) and lower physical activity during pregnancy were linked to increased gallstone occurrence.
Area of Science:
- Obstetrics and Gynecology
- Gastroenterology
- Epidemiology
Background:
- Symptomatic cholelithiasis (gallstones) is a common complication during pregnancy.
- Risk factors for gallstone formation in pregnant populations require further investigation.
Purpose of the Study:
- To investigate the association between demographics, anthropometrics, prenatal physical activity, serum cholesterol, nutrient intakes, and symptomatic cholelithiasis in Northern Plains pregnant women.
Main Methods:
- Cross-sectional study involving 128 Northern Plains pregnant women.
- Data collection at 14 and 26 weeks of gestation and 4 weeks postpartum.
- Statistical analysis including regression to identify predictive factors for cholelithiasis.
Main Results:
- Symptomatic cholelithiasis occurred in 25.8% of Native American and 8.3% of Caucasian pregnant women.
- Pregnant women with cholelithiasis had significantly higher Body Mass Index (BMI) and lower levels of prenatal physical activity.
- History of gallbladder disease, BMI, and prenatal physical activity were significant predictors of cholelithiasis.
Conclusions:
- Higher BMI and reduced physical activity during pregnancy are associated with an increased risk of symptomatic gallstones.
- Ethnic differences in gallstone prevalence were observed, highlighting potential genetic or environmental influences.