Characterization of chicken liver dihydrofolate reductase after purification by affinity chromatography and isoelectric focusing

Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes.

Biochemistry·1993

Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin.

Biochemistry·1992

On the structure selectivity problem in drug design. A comparative study of benzylpyrimidine inhibition of vertebrate and bacterial dihydrofolate reductase via molecular graphics and quantitative structure-activity relationships.

Journal of medicinal chemistry·1989

Interaction of polyglutamyl derivatives of methotrexate, 10-deazaaminopterin, and dihydrofolate with dihydrofolate reductase.

Cancer research·1986

Inhibition of chicken liver dihydrofolate reductase by 5-(substituted benzyl)-2,4-diaminopyrimidines. A quantitative structure-activity relationship and graphics analysis.

Journal of medicinal chemistry·1986

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

The Journal of biological chemistry·1985

The p.V27A variant of l-asparaginase II minimizes glutaminase activity without compromising anti-leukemic function.

Archives of biochemistry and biophysics·2026

NADPH gating and F-actin engagement define the structural bases of MICAL1 autoinhibition and activation.

Archives of biochemistry and biophysics·2026

Hydroxamate formation in Thermochelin biosynthesis.

Archives of biochemistry and biophysics·2026

miR-885-5p regulates fibrogenic phenotypes in TGF-β1-treated LX-2 cells via targeting NR5A2, with clinical association with MAFLD.

Archives of biochemistry and biophysics·2026

Probing transcript RNA G-quadruplexes using an engineered RHAU-RNase HI enzyme.

Archives of biochemistry and biophysics·2026

Stability and Conformational Behavior of Lipase in Propanol-Water Solvent Systems.

Archives of biochemistry and biophysics·2026

Color vision improves foraging success and accelerates reproduction in a jumping spider.

Behavioral ecology : official journal of the International Society for Behavioral Ecology·2026

A centrifuge-free, plate-based protocol to prepare chemically competent Escherichia coli.

Journal of microbiological methods·2026

Electrospun ZIF-8-enhanced fibers for fabric phase extraction of phenytoin from plasma samples followed by high performance liquid chromatography-tandem mass spectrometry analysis.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2026

Dialyzers Outperform Activated Charcoal Filters for Extracorporeal Cisplatin Removal in an Isolated Perfused Porcine Liver Model.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes·2026

Isolation and Expansion of Muscle Satellite Cells Using the Ice-Cold Treatment Method.

Methods in molecular biology (Clifton, N.J.)·2026

Development of a rotating microfluidic device for efficient solid-phase extraction in food analysis.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2026

Related Experiment Videos

Characterization of chicken liver dihydrofolate reductase after purification by affinity chromatography and

Related Concept Videos

Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes.

Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin.

On the structure selectivity problem in drug design. A comparative study of benzylpyrimidine inhibition of vertebrate and bacterial dihydrofolate reductase via molecular graphics and quantitative structure-activity relationships.

Interaction of polyglutamyl derivatives of methotrexate, 10-deazaaminopterin, and dihydrofolate with dihydrofolate reductase.

Inhibition of chicken liver dihydrofolate reductase by 5-(substituted benzyl)-2,4-diaminopyrimidines. A quantitative structure-activity relationship and graphics analysis.

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

The p.V27A variant of l-asparaginase II minimizes glutaminase activity without compromising anti-leukemic function.

NADPH gating and F-actin engagement define the structural bases of MICAL1 autoinhibition and activation.

Hydroxamate formation in Thermochelin biosynthesis.

miR-885-5p regulates fibrogenic phenotypes in TGF-β1-treated LX-2 cells via targeting NR5A2, with clinical association with MAFLD.

Probing transcript RNA G-quadruplexes using an engineered RHAU-RNase HI enzyme.

Stability and Conformational Behavior of Lipase in Propanol-Water Solvent Systems.

Color vision improves foraging success and accelerates reproduction in a jumping spider.

A centrifuge-free, plate-based protocol to prepare chemically competent Escherichia coli.

Electrospun ZIF-8-enhanced fibers for fabric phase extraction of phenytoin from plasma samples followed by high performance liquid chromatography-tandem mass spectrometry analysis.

Dialyzers Outperform Activated Charcoal Filters for Extracorporeal Cisplatin Removal in an Isolated Perfused Porcine Liver Model.

Isolation and Expansion of Muscle Satellite Cells Using the Ice-Cold Treatment Method.

Development of a rotating microfluidic device for efficient solid-phase extraction in food analysis.

Related Experiment Videos

Characterization of chicken liver dihydrofolate reductase after purification by affinity chromatography and...

Related Concept Videos

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Characterization of chicken liver dihydrofolate reductase after purification by affinity chromatography and