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[Androgenetic alopecia].

V del Marmol1, C Jouanique

  • 1Service de Dermatologie, Hôpital Erasme, ULB, Bruxelles.

Revue Medicale De Bruxelles
|November 2, 2004
PubMed
Summary
This summary is machine-generated.

Androgenetic alopecia stems from scalp hair follicle androgen activity, influenced by genetics and hormone levels. Treatments include topical minoxidil, oral finasteride for men, and hormonal therapies for women, with evaluations after six months.

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Area of Science:

  • Dermatology
  • Endocrinology

Context:

  • Androgenetic alopecia (AGA) is a common hair loss condition.
  • Its pathophysiology involves androgen interaction with scalp hair follicles.
  • Genetic predisposition and circulating hormone levels play a role.

Purpose:

  • To outline the physiopathology, diagnosis, and treatment of androgenetic alopecia.
  • To differentiate diagnostic and therapeutic approaches for male and female AGA.
  • To provide an overview of current treatment modalities.

Summary:

  • AGA pathogenesis links to scalp hair follicle androgen activity, influenced by systemic hormones and genetic factors.
  • Classification follows Norwood (male) and Ludwig (female) scales. Hormonal evaluation is crucial for females with hyperandrogenism.

Related Experiment Videos

  • Diagnosis is primarily clinical, aided by trichograms to assess miniaturization and telogen effluvium. Treatments include topical minoxidil (2-5%), oral finasteride (1mg/day) for men, and oestroprogestatives with anti-androgens (cyproterone acetate or spironolactone) for women. Therapeutic efficacy is assessed after 6 months.

    • Impact:

    • Provides a comprehensive overview of AGA management.
    • Highlights the importance of individualized treatment strategies based on sex and hormonal status.
    • Informs clinical practice regarding diagnosis and therapeutic interventions for hair loss.