Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infrared spectroscopy for chemically specific sensing in silicon-based microreactors.

Rachel Herzig-Marx1, K T Queeney, Rebecca J Jackman

  • 1Department of Chemistry, Smith College, Northampton, Massachusetts 01063, USA.

Analytical Chemistry
|November 2, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pathway-Aware Template-Based Retrosynthesis.

Journal of chemical information and modeling·2026
Same author

Machine Learning and Autonomous Systems for Accelerated Synthesis.

Annual review of analytical chemistry (Palo Alto, Calif.)·2026
Same author

Data-driven recommendation of agents, temperature, and equivalence ratios for organic synthesis.

Chemical science·2025
Same author

General Chemically Intuitive Atom- and Bond-Level DFT Descriptors for Machine Learning Approaches to Reaction Condition Prediction.

Journal of chemical information and modeling·2025
Same author

Developing Pharmaceutically Relevant Pd-Catalyzed C-N Coupling Reactivity Models Leveraging High-Throughput Experimentation.

Journal of the American Chemical Society·2025
Same author

ASKCOS: Open-Source, Data-Driven Synthesis Planning.

Accounts of chemical research·2025
Same journal

Machine Learning-Assisted Label-Free SERS Decoding of Mitochondrial Molecular Dynamics in Ovarian Granulosa Cells during Aging.

Analytical chemistry·2026
Same journal

Revealing the Regulatory Interplay of NHE1 mRNA and Na<sup>+</sup> in Cancer Cells Using a DNA Nanosensor.

Analytical chemistry·2026
Same journal

Towards Cellular Resolution of Tryptic Peptides in Tissue Sections by MALDI MS Imaging: A Focus on Enzyme Application and Reproducibility.

Analytical chemistry·2026
Same journal

Bioinspired Bilayer Hydrogel Colorimetric Sensor Array for Low-Temperature Food Freshness Analysis.

Analytical chemistry·2026
Same journal

Quartz Crystal Microbalance-Based Point-of-Care Testing Systems: Principles, Device Design, and Applications.

Analytical chemistry·2026
Same journal

Heterojunction Gate-Empowered OPECT Aptasensing: A Valid Protocol for Realizing High Current Gain at Low Electron Donor Dependency.

Analytical chemistry·2026
See all related articles

Silicon microreactors integrated with Fourier transform infrared (FT-IR) spectroscopy enable versatile chemical detection. This approach allows for probing both solution-phase and surface-bound chemical reactions using inexpensive fabrication methods.

Area of Science:

  • Analytical Chemistry
  • Chemical Engineering
  • Materials Science

Background:

  • Fourier transform infrared (FT-IR) spectroscopy is a powerful analytical technique.
  • Silicon-based microreactors offer advantages in cost-effective fabrication and small-scale chemical processing.

Purpose of the Study:

  • To integrate FT-IR spectroscopy with silicon-based microreactors for chemical species detection.
  • To leverage microfabrication techniques for creating versatile chemical analysis platforms.
  • To demonstrate the applicability of this integrated system for studying chemical transformations.

Main Methods:

  • Fabrication of silicon and glass microreactors using standard microfabrication and selective etching.
  • Integration of multiple internal reflection (MIR) FT-IR spectroscopy with the microreactors.

Related Experiment Videos

  • Analysis of solution-phase and surface-bound chemical reactions within the microreactors.

    • Main Results:

    • Successful integration of MIR-FT-IR spectroscopy with silicon microreactors.
    • Demonstration of detection for a wide range of chemical species.
    • Accurate probing of both solution-phase and surface-bound chemical transformations.
    • Successful application to study acid-catalyzed ethyl acetate hydrolysis kinetics and surface-tethered amine amidization.

    Conclusions:

    • The integrated MIR-FT-IR spectroscopy and silicon microreactor system is a versatile and cost-effective platform for chemical analysis.
    • This approach allows for the study of diverse chemical reactions, including kinetics and surface chemistry.
    • The use of silicon microreactors enables access to a broad spectral range for comprehensive chemical probing.