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Published on: June 27, 2025
Heterotopic pregnancy in a natural conception cycle presenting as hematometra
Po-Jen Cheng1, Ho-Yen Chueh, Jian-Tai Qiu
1Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan. pjcheng@cgmh.org.tw
Background:
Heterotopic pregnancy is a rare event in natural conception cycles. Diagnosis of heterotopic pregnancy requires a high index of suspicion. Described herein is a reported case of a heterotopic pregnancy presenting as hematometra.
Case:
A young, multiparous woman, with her last menstrual period 6 weeks before presentation, complained of a dark reddish-brown vaginal discharge and progressive left lower-quadrant discomfort during early pregnancy following a natural conception cycle. An intrauterine mass was observed, and subsequently a heterotopic pregnancy complicated by hematometra was diagnosed with the help of transvaginal ultrasonography and 3-dimensional power Doppler ultrasound angiography.
Conclusion:
Women with intrauterine fluid accumulation during pregnancy may be at risk for coexistent ectopic pregnancy. High resolution transvaginal color Doppler sonography may be useful to identify a heterotopic pregnancy preoperatively.
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