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Updated: Aug 21, 2026
Thin-layer Chromatographic (TLC) Separations and Bioassays of Plant Extracts to Identify Antimicrobial Compounds
Published on: March 27, 2014
Antimicrobial screening and quantitative determination of benzoic acid derivative of Gomphrena celosioides by
Rute Mendonça Xavier de Moura1, Paulo Sérgio Pereira, Ana Helena Januário
1Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, 14040-020 Ribeirão Preto, São Paulo, Brazil.
Abstract:
The antimicrobial activity of ethanolic extract and pure compounds of Gomphrena celosioides have been screened by Kirby-Bauer method. Quantitative determination of 4-hydroxy-3-methoxy-benzoic acid in stems, leaves, flowers and roots was established by TLC-densitometry. Results showed significant activity against Staphylococcus aureus and Salmonella typhi. There were no significant differences in the determined benzoic acid derivative.
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