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A functional study of caustic strictures of the esophagus in children

E A L Da-Costa-Pinto1, T K Dorsa, A Altimani

  • 1Departamento de Pediatria, Faculdade de Ciências Médicas, Universidade Estadual de CampinasCampinas, SP, Brasil. elicostapinto@uol.com.br

Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
|November 2, 2004
PubMed

Insights

Children with caustic strictures exhibit abnormal esophageal motility, impacting swallowing function. These esophageal motor function abnormalities are linked to the severity of the stricture and scarring.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Motility Disorders

Background:

  • Caustic strictures in children can lead to significant esophageal dysfunction.
  • Understanding the underlying motor abnormalities is crucial for managing dysphagia.

Purpose of the Study:

  • To evaluate esophageal motor function in pediatric patients with caustic strictures.
  • To correlate manometric and scintigraphic findings with clinical symptoms.

Main Methods:

  • Esophageal manometry using a water-infusion system.
  • Radionuclide transit studies with 99mTc pertechnetate.
  • Comparison with a control group of healthy children.

Main Results:

  • Patients with caustic strictures showed non-peristaltic, low-amplitude, long-duration esophageal waves.
  • Significantly lower mean wave amplitude and longer mean wave duration were observed compared to controls.
  • Delayed esophageal transit and an association between dysphagia and manometry/scintigraphy abnormalities were noted.

Conclusions:

  • Dysphagia in pediatric caustic strictures is primarily caused by esophageal motility abnormalities.
  • These abnormalities are closely related to the extent of esophageal scarring.

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