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Published on: April 9, 2013
Infection prophylaxis of gunshot wounds using probiotics
1Department of Trauma Surgery, Orthopaedics and Military Surgery, Orenburg State Medical Academy, Russia. bacoren@rambler.ru
Objective:
To report a new method of surgical infection prophylaxis for postoperative gunshot wounds to the extremities.
Method:
Gunshot wounded animals were divided into three groups: treatment (probiotic Sporobacterin), antibiotic (cephalosporin cefamezin) and control (no treatment). Histological studies of wound-bed tissue were taken on days 1, 3, 5 and 10 of the study.
Results:
The probiotic administered per os was more effective than antibiotics for prophylaxis of surgical infection.
Conclusion:
The probiotic's effect is based on the natural defence mechanism activated after injury--the bacterial translocation of saprophytic bacteria from the gut to the wound.
Declaration Of Interest:
None.
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