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Updated: Aug 21, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Balanced de novo translocation t(6;7)(p25;q31) and cleft palate as an isolated finding
S Balci1, E Aypar, Y Aydin Son
1Department of Clinical Genetics, Hacettepe University, Ihsan Doğramaci Children's Hospital, 06100 Sihhiye, Ankara, Turkey. sbalci@hacettepe.edu.tr
Abstract:
We report a prenatally diagnosed balanced de novo translocation t(6;7)(p25;q31). Physical examination of the baby born at term revealed only a posterior cleft palate. Laboratory examinations and radiologic investigations were found normal. Two years follow-up of the patient showed her mental and motor development was appropriate with her age. Our report is the first observation on balanced de novo translocation t(6;7)(p25;q31) and cleft palate. Association of this translocation and cleft palate has not been reported previously.
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