[Pathologic-anatomic diagnosis of endocrine neoplasms: new trends and applications]

The pathologic-anatomical diagnosis of endocrine diseases mainly relies on established techniques of histology and cytology. Additional immunhistochemical tests an the expression analysis may lead to a higher specificity of the morphological diagnosis. For thyroid tumours so-called high-throughput methods have been established in clinical routine successfully. Calcitonin screening tests can be performed routinely in patients with or without an increased risk of familiar dominance. For the neuroendocrine neoplasms of the pancreas and the gastrointestinal tract a new WHO classification has been established.