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Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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[Administration of activated recombinant factor VII (novo seven) for the control of massive bleeding in gynecology]

S Tanchev, F Pandurski, A Georgiev

    Akusherstvo I Ginekologiia
    |November 3, 2004
    PubMed

    We report our clinical opinion for recombinant activated factor VII (NovoSeven, Novo Nordisk, Copenhagen, Denmark) administration in gynecology patients with massive haemorrhage. 3 women with gynecology deseases and severe bleeding in recieved NovoSeven in bolus IV. The blood loss and laboratory changes in hematology and haemostasis parameters are monitored. The bleeding was ceased in all cases. Decrease in values of Hb, Er and PTT was noted. The use of recombinant factor VIIA in gynecology patients with severe bleeding is effective and safe enough and could be an alternative to the extreme surgical procedures.

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