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Updated: Aug 5, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
The head-up tilt test -- a cause of myocardial infarction
S I Goolamali1, V L Loh, M Sopher
1Cardiology Department, St George's Hospital, Blackshaw Road, Tooting, London SW17 OQT, United Kingdom. mediderm@btinternet.com
Abstract:
INFARCTION: A 74-year-old man with no known ischaemic heart disease presented to the Cardiology Department with a history of multiple episodes of pre-syncope. During a head-up tilt test to investigate a neurocardiogenic cause, after glyceryl trinitrate provocation he became profoundly hypotensive and unwell. Subsequent ECGs and Troponin-T levels confirmed a Non ST-Elevation Myocardial Infarction. Angiography confirmed coronary artery disease. This case highlights a rare complication of tilt testing and emphasises that the test is not without risk.
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