[Nutritional status of opiate-dependent persons before and during methadone maintenance therapy]

The aim of the study was to evaluate the nutritional status of opiate dependent patients who where classified to participate in the methadone maintenance treatment and to give the answer to the question how the nutritional status of these patients was changing during this programme. We examined 48 persons (12 women aged 21-37 years and 36 men aged 20-46 years). All of them were participants of the methadone maintenance treatment. The patients were examined three times: first time just before the methadone treatment, then after 2 months and third time after 9 months of treatment. The anthropometrics measurement: body weight and height (it allowed us to calculate the BMI), two skin fat folds and the measurements of the body composition (using the bioimpedance method) were performed. The changes between the results of subsequent examination were tested using the t-Student test. As a result of the first examination we showed out that the majority of patients had a proper nutritional status evaluated by BMI. Poor nutritional status has been more often found than excessive nutritional status among examined patients, especially in the group of women. During the nine months of methadone maintenance treatment the statistically significant growth of body weight was observed and it derived from the increasing fat body mass and muscle mass. As a result of that we noticed the diminishing number of underweight people. More of examined people had overweight and in the group of men even obesity.