Related Experiment Video
Updated: Aug 21, 2026

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
Published on: April 1, 2015
The role of thrombospondin-1 in human disease
Nowokere Esemuede1, Taeseung Lee, Daphne Pierre-Paul
1Yale University School of Medicine, New Haven, Connecticut, USA.
Abstract:
Thrombospondin-1 (TSP-1) is a large matricellular glycoprotein secreted by many cell types. It is a component of the extracellular matrix during active and subacute processes. Due to TSP-1's ability to interact with a variety of matrix proteins and cell-surface receptors, controversy exists about its conflicting functions. In this review, we will discuss the role of TSP-1 in human disease.
Related Concept Videos
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Intracellular Signaling Affects Focal Adhesions
Some...
Clot Retraction and Fibrinolysis
Venous Thrombosis I: Introduction
Cytoskeletal Linker Proteins - Plakins
TGF - β Signaling Pathway
